Test Report
Product Name: Gong Ming Anti-HIV Intravenous Injection Liquid (GMA-HIV)
Ref. No.:970301
Submitted By: Gong Ming Pharmaceutical Co. Ltd. (Heilong Jiang Province)
Test Purpose: Assess inhibitory effects of GMA-HIV on HIV-1
Submission Date: April 1997
Test Methodology
Setup
- Different concentrations of GMA-HIV in a 96 well plate containing MT4 cells
- Add 100 TCID50 HIV-1 suspension liquid
- Conditions of Culture
- Study ¨C GMA-HIV & MT4 cells in HIV-1 suspension liquid
Control ¨C MT4 cells in HIV-1 suspension liquidProcedure
- Observe GMA-HIV toxicity effects on MT4 cells
- Observe GMA-HIV inhibitory effects on HIV-1 mutagenic capability
- Repeat the test 3 times
Test Results:
- GMA-HIV at a concentration of 25 mg/ml is lethal to 50% of MT4 cells
- GMA-HIV at a concentration of 12.5 mg/ml or greater can inhibit mutagenic effects of HIV-1 on MT4 cells
Conclusion: From this experiment, GMA-HIV has certain inhibitory effect (in vitro) on HIV-1.
Lab Technician: Wang, Hong Xia
Auditor: Li, Jing Yun
Date: 1997 May 15
People¡¯s Liberation Army Confirmatory Diagnostic Laboratory of AIDS
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