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Clinical Reports  
HBV CLinical Reports
Chinese People's Liberation Army 302 Hospital  

Ninth Section of Liberation Army 302 Hospital
We have cured thirty patients of Chronic using Hepatitis Kang Injection Liquid and Hepatitis B Kang Capsules Offered by Liberation Army 211 Hospital. The recent report of cure observation is following.

Material and Ways

1 .Case Circumstance
Sixty patients of our hospital, of which, treatment group and contrast group respectively include 30 persons, according to the diagnosis standard which is revised on the National Hepatitis Meeting in 1990.

Two case¨ circumstance as follows:
List The general Circumstance of Two Group of Case

sex

Average Age
(year)


Course of Disease

Diagnosis

Male

Female

CPH
CAH

Treatment Group

26

4

32.8

Two Months-11Years

13

17

Contrast Group

25

5

35.1

Two Months-Nine Years

10

20

2.The Method of cure
TreatmentGroup: Hepatitis B kang Injection Liquid adding 10% glucose injection liquid 250ml, one time a day, at the same time takes four capsules, three months.

Contrast Group: Use general medicine of protecting liver, the course of cure is three months.

3. Observation Index:
Check the liver¨s function before curing ,per Half month, check ELISA per month, and part of the cases, HBV-DNA are checked .

consequence:

1.The effect of Hepatitis B Kang acting on Liver¨s function

List 2 is the contrast of two group patients ACT recoving ratio, it has no obviously difference P>0.05

List Å The contrast of two group patients¨ ACT recovering ratio

Abnormal cases

Recovering cases

Recovering Ratio

Treatment group

30

22

73.33

Contrast Group

28

20

71.43

P>0.05
                                 
2.Changes of HBsAg、HBeAg and HBV-DNA in two group.

List 3 is changes of HBsAG, HBeAg and HBV-DNA in two group. It can be seen from List 3 that HBeAg and HBV-DNA converting negative ratio in the group of using Hepatitis B Kang Capsules are much heavier difference between two groups (P<0.05)

List ‰ is changes of HBsAg、HbBeAg and HBV-DNA

The number of HbsAg converting Negtive (%)

the number of HbsAg titerd- ropping(%)

the number of HbeAg converting negative
the number of HbeAg titerd- ropping

the number of HBV-DNA conce- rning negative

Curing Group

1/30  3.33

6/30 20.0

12/26 46.5* 6/26 23.08

9/15 60.0*

Contrast Group

0/30   /

2/30 6.67

2/27 7.14

4/18 22.22

The contrast of two group(P<0.05)

Summary

Hepatitis B Kang Capsules are pure Chinese traditional medical preparation developed by Heilongjiang Province Recovering Company, on the basis of Chinese traditional medical theory and modern medical theory, Through research of the test of epidemic disease and pharmacology, this medicine can directly act on hepatitis virus to protect liver cells, promote Liver cells to regenerate, strengthen immune function of body, accelerate protein to compound, and correct protein in verse. This product can produce heavier effect to HBsAg and HBeAg, and there is apparent effect of dropping enzyme and bigger capacity of regenerating liver cells, After this group(30 cases) are cared for three month, the effect can be attained that the ratio of serum ACT restoring normal reaches 73.33%, the ratio of HBeAg converting negative reaches 46.15%, and the ratio of ABV-DNA converting negative reaches 60.0% From which it can be illustrated that this medicine has apparent restraining effect to duplicating of hepatitis B virus and better effect of dropping enzyme. Addition of it, we also observe that HBsAg and HBeAg titer dropping of them obviously lowers, though HbsAg and HBeAg of many patients cured for three months doesn¨t convert negative. If time and course of that is prolonged, whether can get better curative effect need Farther observation.

This product is pure Chinese traditional medical preparation, has no side effect, and its price is not much expensive than other medicines, so this product is one of many prospective medicines of curing hepatitis. It is worth to further spread and research.