Chinese People's Liberation Army 211 Hospita¡¡Wang Kongjun
Harbin Red Cross Children¡¯s Hospital¡¡¡¡¡¡¡¡¡¡Liu Fengying
Through using the YiGankang preparation£¨Heilongjiang province Gongming pharmaceutical Co., Ltd produce£©to cure the patients that infect the virus of hepatitis B and hepatitis C, the medicine has the cured 30 cases of hepatitis C and 20 contrast cases, the report is as follows:
1. Material and Method
1.1¡¡The Circumstances of Case:
The patients of hepatitis C are diagnosed by clinic or inpatient department the clinical diagnosis according to the revise standards of Beijing the whole country¡¯s fifth academic meeting about infection and parasitosis in 1995. There are 30 cases of hepatitis B treatment group, 26 cases of chronic hepatitis C, 4 cases of infecting hepatitis B and hepatitis C, 22 cases of IFN treatment group, they are all chronic hepatitis C, anti-HCV (ELISA) are (+), HCVRNA are (+), ALT is one time higher the normal.
Two Groups' Comparison in General Circumstance
|
Sex |
Age |
The Course of Chronic Hepatitis C |
Diagnosis |
|
M |
F |
|
|
The Chronic Hepatitis C |
Hepatitis B and Hepatitis C |
YiGankang |
24 |
6 |
16-72 |
6months-13years |
26 |
4 |
IFN |
20 |
2 |
14-59 |
1year-9years |
22 |
0 |
1. 2 Treatment Method:
Treatment Group: 10ml YiGankang injection is added to 250ml 5% Glucose, Qdivgtt, at the same time takes 8 YiGankang Capsules, 3 times a days continuum usually three months didn¡¯t cure the patients stop the medicine two weeks, then continue, the curative course is 6 months.
Contrast Group (a-2b) IFN 3000000 units Qdim once a day, then once intwo days after two weeks. 6 months are a curative course.
Before and after treatment, all cases should have a check of liver function, anti-HCV, HCVRNA, the patients who are infected by hepatitis B and C, should be checked two and a half hepatitis B standard things and HBVDNA.
Consequence
1. The effect to liver function
The obvious difference of two groups of patients ALT recovered rates occur P<0.01
Comparison between two group of ALT recovered rate
|
Before Cure |
After Cure |
RecoveredRate(%) |
YiGankang |
30 |
23/30 |
76.67 |
IFN |
22 |
6/22 |
27.27 |
T |
T=6.991644 |
|
P<0.01 |
2. The comparison of two groups of patients¡¯ HCVRNA changing(-), YiGankang group.
Change(-) 16 cases of HCVRNA, in which there are 14 cases chronic hepatitis C, 2 cases of infecting hepatitis B and C, the total rate to change (-) is 53%, change(-) 6 cases IFN, the changing (-) rate totally amounts to 27%, the ¡°T¡± test of two group, T=3.752776, p<0.01, the difference is obvious .
comparison of the rate¡¯s of HCVRNA changing(-) of two group
|
HCVRNA |
RecoveredRate(%) |
Hepatitis B(n=30) |
16/30 |
53 |
IFN(n=22) |
6/22 |
21 |
¡°T¡± Test |
T=3.752770 |
P<0.01 |
After using YiGankang for six months, the group¡¯s HCVRNA is still (+), there are 7 cases stop the medicine for two weeks, then continue hepatitis B for 2 months, in which 4 cases¡¯ HCVRNA changed(-), 6 case¡¯ ALThave become normal, the patients of IFN group that HCVRNA has not changed(-), 6 cases¡¯ changed using YiGankang, 3 cases¡¯ HCVRNA changed(-), 5 case¡¯ ALT have become normal, the corresponding symptom is improved.
Discussion
YiGankang preparation includes Hepatitis B Injection and Hepatitis B Capsule, studied for a few years by Hei Longjiang Gongming Pharmaceutical Co., Ltd, according to the theory of the Chinese traditional medicine and modern medicine, through the tests of epidemiology and pathology, is proved to have no side-effect. During the clinical observation of the group, noside effect is found. The preparation, intravenously, can directly act on hepatitis virus, prevent the duplication and metabolism, finally kill the virus. YiGankang preparation has the function to improve blood circumstance of the blood, increase the liver¡¯s blood flowing quantity and strengthen cells¡¯ oxidizing process, improve the metabolism of ferment and sugar to pretest the liver¡¯s cell, promote the liver¡¯s cell to renew, strengthen the body¡¯s immunity function, promote the body clear hepatitis virus further. The group using YiGankang and IFN has all get the good curative effect, but YiGankang is safe and cheap, has no side-effect, if cure for a long time, the curative effect is better, IFN can be delayed the time to strengthen the curative effect and prevent the reaction.
References
1. Liu Fengying,Wang Kongjun: The Observation of the curative effect of YiGankang curing virus hepatitis and cirrhosis.China Pharmacology Bulletin 1996. 12(8): 80
2. Si Congwen, Tian Gengshan, Wu Shaming: The observation of the curative effect of three curatives method to cure chronicle Hepatitis B. China Internal Medicine Magazine 1997, 36(10): 661
3. Chen Guoliang, Yan Jianghua, and Ouyang Lijuan: The observation of curative effect to hepatitis with combined interferon. China Liver Disease Magazine 2000. 1(8): 56
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